For blepharospasm treatment, reconstituted Botulax® 50/100/200 (refer to Dilution Table) should be injected using a sterile 27-30 gauge needle without electromyographic guidance. The initial recommended dose ranges from 1.25 to 2.5 units (0.05 mL to 0.1 mL volume at each site). This is injected into specific areas around the eyes. Typically, you will see the initial effects within three days, with the peak effect occurring at one to two weeks post-treatment. The effects usually last for approximately three months, after which the procedure can be repeated. If the initial treatment's response is considered insufficient (lasting less than two months), the dose may be increased by up to two-fold. However, it is generally not beneficial to inject more than 5.0 units per site. Some tolerance may develop if treatments are administered more frequently than every three months, and long-lasting effects are rare. The total cumulative dose of Botulax® 50/100/200 in a 30-day period should…
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